circRNA basic information
circBase ID: -
Name: hsa_circ_ANKIB1
Synonym: circ_ANKIB1
Host Gene: hsa-miR-19b
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal human osteoblast (hFOB 1.19), human osteosarcoma cell lines (MG-63, 143B, Saos-2, U-2 OS, HOS)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SOCS3, STAT3
Associated microRNA: hsa-miR-19b
Biological function: promote osteosarcoma cell growth and invasion.
Molecular mechanism: circ_ANKIB1 could affect the STAT3 pathway and osteosarcoma cell growth and invasion by enhancing the regulation of hsa-miR-19b on the downstream target gene SOCS3
Survival: -
Supported No.:
 3
Description:

circ_ANKIB1 could affect the STAT3 pathway and osteosarcoma cell growth and invasion by enhancing the regulation of miR-19b on the downstream target gene SOCS3.
Other information
Title:

Circ_ANKIB1 stabilizes the regulation of miR-19b on SOCS3/STAT3 pathway to promote osteosarcoma cell growth and invasion.

Journal: Hum Cell
Published: 2019/11/2
PubMed ID: 31667786