circRNA basic information
circBase ID: -
Name: hsa_circ_MYO10
Synonym: -
Host Gene: hsa-miR-370-3p
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: RUVBL1
Associated microRNA: hsa-miR-370-3p
Biological function: promotes the proliferation
Molecular mechanism: promote chromatin remodeling and thus enhances the transcriptional activity of beta-catenin/LEF1 complex
Survival: -
Supported No.:
 1
Description:

CircMYO10 promotes osteosarcoma progression by regulating miR-370-3p/RUVBL1 axis to promote chromatin remodeling and thus enhances the transcriptional activity of beta-catenin/LEF1 complex.
Other information
Title:

CircMYO10 promotes osteosarcoma progression by regulating miR-370-3p/RUVBL1 axis to enhance the transcriptional activity of beta-catenin/LEF1 complex via effects on chromatin remodeling.

Journal: Mol Cancer
Published: 2019/10/31
PubMed ID: 31665067