circRNA basic information
circBase ID: -
Name: hsa_circ_C3P1
Synonym: -
Host Gene: hsa-miR-21
 
 
 
Disease basic information
DO ID:
 263
DO name: kidney cancer
Disease details: kidney cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: human KC cells (A498, ACHN)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: PTEN and PI3K/AKT and NF- kB pathways
Associated microRNA: hsa-miR-21
Biological function: declined cell viability, migration, and invasion and caused apoptosis
Molecular mechanism: negatively regulated hsa-miR-21
Survival: -
Supported No.:
 1
Description:

circC3P1 restrained KC cell growth, migration, and invasion by regulating miR-21/PTEN axis and inactivating PI3K/AKT and NF-kappaB signaling pathways.
Other information
Title:

Circular RNA circC3P1 restrains kidney cancer cell activity by regulating miR-21/PTEN axis and inactivating PI3K/AKT and NF- kB pathways.

Journal: J Cell Physiol
Published: 2019/10/24
PubMed ID: 31643094