circRNA basic information
circBase ID: -
Name: hsa_circ_LARP4
Synonym: -
Host Gene: hsa-miR-424
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-424
Biological function: elevated the chemosensitivity of MG63 cells to cisplatin and doxorubicin but not methotrexate
Molecular mechanism: sponging microRNA-424
Survival: better
Supported No.:
 1
Description:

Circ-LARP4 high expression correlates with decreased Enneking stage and prolonged survival profiles, and it elevates chemosensitivity to cisplatin and doxorubicin via sponging miR-424 in osteosarcoma.
Other information
Title:

Circular RNA LARP4 correlates with decreased Enneking stage, better histological response, and prolonged survival profiles, and it elevates chemosensitivity to cisplatin and doxorubicin via sponging microRNA-424 in osteosarcoma.

Journal: J Clin Lab Anal
Published: 2019/10/24
PubMed ID: 31642110