circRNA basic information
circBase ID: -
Name: hsa_circ_RhoC
Synonym: -
Host Gene: hsa-miR-302e
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: VEGFA
Associated microRNA: hsa-miR-302e
Biological function: increased cell viability, migration and invasion ability
Molecular mechanism: functioning as a hsa-miR-302e sponge to positively regulate VEGFA
Survival: -
Supported No.:
 1
Description:

the oncogenic effect of RhoC in ovarian cancer is at least in part due to circRhoC, which functions not only as a miR-302e sponge to positively regulate VEGFA protein expression, but may also directly bind and modulate VEGFA expression.
Other information
Title:

CircRhoC promotes tumorigenicity and progression in ovarian cancer by functioning as a miR-302e sponge to positively regulate VEGFA.

Journal: J Cell Mol Med
Published: 2019/10/23
PubMed ID: 31639291