circRNA basic information
circBase ID: -
Name: hsa_circ_NSUN2
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: promote colorectal liver metastasis
Molecular mechanism: modulates cytoplasmic export and stabilizes HMGA2
Survival: -
Supported No.:
 3
Description:

N6-methyladenosine modification of circNSUN2 modulates cytoplasmic export and stabilizes HMGA2 to promote CRC LM, and suggest that circNSUN2 could represent a critical prognostic marker and/or therapeutic target for the disease.
Other information
Title:

N(6)-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis.

Journal: Nat Commun
Published: 2019/10/18
PubMed ID: 31619685