circRNA basic information
circBase ID: hsa_circ_0070269
Name: hsa_circ_PLAC8
Synonym: -
Host Gene: hsa-miR-182
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human HCC cell lines (Hep-3B, SMMC_7721, HepG2, PLC, Huh_7), normal liver cell line (LO2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: NPTX1
Associated microRNA: hsa-miR-182
Biological function: suppressed proliferation and invasion
Molecular mechanism: increased NPTX1 expression via sponging hsa-miR-182 in HCC cells, which inhibited aggressive tumor behavior
Survival: -
Supported No.:
 1
Description:

hsa_circ_0070269 increased NPTX1 expression via sponging miR-182 in HCC cells, which inhibited aggressive tumor behavior.
Other information
Title:

Hsa_circ_0070269 inhibits hepatocellular carcinoma progression through modulating miR-182/NPTX1 axis.

Journal: Biomed Pharmacother
Published: 2019/10/14
PubMed ID: 31606623