circRNA basic information
circBase ID: -
Name: hsa_circ_CCDC66
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HCT116, HT-29
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: promotes cell proliferation, migration, and invasion
Molecular mechanism: -
Survival: poor
Supported No.:
 4
Description:

Gain-of-function and loss-of-function studies in CRC cell-lines demonstrated that circCCDC66 controlled multiple pathological processes, including cell proliferation, migration, invasion, and anchorage-independent growth.
Other information
Title:

Noncoding Effects of Circular RNA CCDC66 Promote Colon Cancer Growth and Metastasis.

Journal: Cancer Res
Published: 2017/3/3
PubMed ID: 28249903