circRNA basic information
circBase ID: hsa_circ_0000218
Name: -
Synonym: circ_0000218
Host Gene: hsa-miR-139-3p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal colon epithelial cell Line (NCM460), human CRC cell line (SW480, SW620, KM12, SW116, HCT116)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: RAB1A
Associated microRNA: hsa-miR-139-3p
Biological function: enhanced the proliferation and metastasis
Molecular mechanism: upregulated RAB1A and promoted CRC proliferation and metastasis via sponging hsa-miR-139-3p
Survival: poor
Supported No.:
 1
Description:

Circ_0000218 upregulated RAB1A and promoted CRC proliferation and metastasis via sponging miR-139-3p.
Other information
Title:

Circ_0000218 plays a carcinogenic role in colorectal cancer progression by regulating miR-139-3p/RAB1A axis.

Journal: J Biochem
Published: 2019/10/11
PubMed ID: 31598673