circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: hsa-miR-149
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal human bronchial epithelial cell line (16HBE), NSCLC adenocarcinoma cell lines (SPC-A1, A549, NCI-H1299, NCI-H1650)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FOXM1
Associated microRNA: hsa-miR-149
Biological function: induces cell proliferation and inhibits apoptosis
Molecular mechanism: sponging hsa-miR-149
Survival: -
Supported No.:
 4
Description:

circHIPK3 regulates the function of NSCLCs through miR-149-mediated FOXM1 expression regulation.
Other information
Title:

Circular RNA HIPK3 induces cell proliferation and inhibits apoptosis in non-small cell lung cancer through sponging miR-149.

Journal: Cancer Biol Ther
Published: 2019/10/11
PubMed ID: 31597523