circRNA basic information
circBase ID: hsa_circ_0021977
Name: -
Synonym: circ_0021977
Host Gene: hsa-miR-10b-5p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human CRC cell lines (SW480, HCT8, HCT116, DLD1), human colonic normal epithelial cell line (HCoEpic)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: P21 and P53
Associated microRNA: hsa-miR-10b-5p
Biological function: suppresses proliferation, migration, and invasion
Molecular mechanism: circ_0021977/hsa-miR-10b-5p/P21 and P53 regulatory axis
Survival: -
Supported No.:
 1
Description:

circ_0021977/miR-10b-5p/p21&p53 regulatory axis suppresses proliferation, migration, and invasion by CRC cells.
Other information
Title:

The circ_0021977/miR-10b-5p/P21 and P53 regulatory axis suppresses proliferation, migration, and invasion in colorectal cancer.

Journal: J Cell Physiol
Published: 2019/10/9
PubMed ID: 31595500