circRNA basic information
circBase ID: hsa_circ_0016070
Name: hsa_circ_ATP2B4
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
14557
DO name: primary pulmonary hypertension
Disease details: pulmonary arterial hypertension
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
M
Detected method confidence Low
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: increased cell viability and decreased the number of cells arrested in the G1/G0 phase
Molecular mechanism: -
Survival: -
Supported No.:
2
Description:

hsa_circ_0016070 was associated with vascular remodeling in PAH by promoting the proliferation of pulmonary artery smooth muscle cells (PASMCs) via the miR-942/CCND1.

Other information
Title:

Circular RNA hsa_circ_0016070 Is Associated with Pulmonary Arterial Hypertension by Promoting PASMC Proliferation.

Journal: Mol Ther Nucleic Acids
Published: 2019/10/9
PubMed ID: 31593832