circRNA basic information
circBase ID: -
Name: hsa_circ_ERCC2
Synonym: -
Host Gene: hsa-miR-182-5p
 
 
 
Disease basic information
DO ID:
 90
DO name: degenerative disc disease
Disease details: intervertebral disc degeneration
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: SIRT1
Associated microRNA: hsa-miR-182-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

The effects of circERCC2 on NPCs and IVDD rat model were mediated by miR-182-5p/SIRT1 axis.
Other information
Title:

CircERCC2 ameliorated intervertebral disc degeneration by regulating mitophagy and apoptosis through miR-182-5p/SIRT1 axis.

Journal: Cell Death Dis
Published: 2019/10/5
PubMed ID: 31582722