circRNA basic information
circBase ID: -
Name: hsa_circ_TSPAN4
Synonym: circ-TSPAN4
Host Gene: hsa-miR-665
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal human bronchial epithelial cell line, LUAD cell lines (A549, H1975, H1993, PC9, H1299)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ZEB1
Associated microRNA: hsa-miR-665
Biological function: promotes lung adenocarcinoma metastasis
Molecular mechanism: upregulating ZEB1 via sponging hsa-miR-665
Survival: -
Supported No.:
 1
Description:

Circ-TSPAN4 plays a pivotal metastasis-promoting role in LUAD through acting as a sponge for miR-665 and upregulating ZEB1.
Other information
Title:

Circular RNA circ-TSPAN4 promotes lung adenocarcinoma metastasis by upregulating ZEB1 via sponging miR-665.

Journal: Mol Genet Genomic Med
Published: 2019/10/2
PubMed ID: 31573758