circRNA basic information
circBase ID: -
Name: -
Synonym: circ949
Host Gene: mmu-miR-29b-2-5p
 
 
 
Disease basic information
DO ID:
3770
DO name: pulmonary fibrosis
Disease details: pulmonary fibrosis
Species: mouse
Species details: mouse
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
S
Detected method confidence Low
Expression pattern:
UP
Associated gene: STAT3
Associated microRNA: mmu-miR-29b-2-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
1
Description:

The fibrotic function of lnc949 depended on its host gene FKBP5. circ949 and circ057 formed a regulatory network with lnc865 and lnc556 to simultaneously regulate miR-29b-2-5p targeting STAT3 phosphorylation.

Other information
Title:

Crosstalk of mRNA, miRNA, lncRNA, and circRNA and Their Regulatory Pattern in Pulmonary Fibrosis.

Journal: Mol Ther Nucleic Acids
Published: 2019/9/29
PubMed ID: 31561125