circRNA basic information
circBase ID: hsa_circ_0053277
Name: hsa_circ_NRBP1
Synonym: -
Host Gene: hsa-miR-2467-3p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human CRC cell lines (HCT116, SW480, SW620, HT29, RKO, LOVO), normal human colonic epithelial cell line (HCoEpiC)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-2467-3p
Biological function: promote cell proliferation, migration, and epithelial-mesenchymal transition (EMT)
Molecular mechanism: positively regulated MMP14 expression while hsa-miR-2467-3p negatively regulated MMP14 expression.
Survival: -
Supported No.:
 1
Description:

hsa_circ_0053277 facilitated the development of CRC by sponging miR-2467-3p to upregulate MMP14 expression.
Other information
Title:

Circular RNA hsa_circ_0053277 promotes the development of colorectal cancer by upregulating matrix metallopeptidase 14 via miR-2467-3p sequestration.

Journal: J Cell Physiol
Published: 2019/9/25
PubMed ID: 31549406