circRNA basic information
circBase ID: -
Name: hsa_circ_FBXW7
Synonym: -
Host Gene: hsa-miR-197-3p
 
 
 
Disease basic information
DO ID:
 60081
DO name: triple-receptor negative breast cancer
Disease details: triple-negative breast cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: MCF-10A, MCF-7, T47D, BT474, SKBR-3, MDA-MB-453, MDA-MB-468, MDAMB-231, BT549, HCC38, 4T1, MA-891
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: FBXW7
Associated microRNA: hsa-miR-197-3p
Biological function: inhibited cell proliferation, migration, and tumor growth
Molecular mechanism: sponges hsa-miR-197-3p and encodes the FBXW7-185aa protein to suppress TNBC progression through upregulating FBXW7 expression.
Survival: better
Supported No.:
 1
Description:

circFBXW7 sponges miR-197-3p and encodes the FBXW7-185aa protein to suppress TNBC progression through upregulating FBXW7 expression.
Other information
Title:

circFBXW7 Inhibits Malignant Progression by Sponging miR-197-3p and Encoding a 185-aa Protein in Triple-Negative Breast Cancer.

Journal: Mol Ther Nucleic Acids
Published: 2019/9/20
PubMed ID: 31536884