circRNA basic information
circBase ID: -
Name: hsa_circ_LDLRAD3
Synonym: -
Host Gene: hsa-miR-137-3p
 
 
 
Disease basic information
DO ID:
 1793
DO name: pancreatic cancer
Disease details: pancreatic cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human pancreatic cancer cell lines (SW1990, BXPC-3, Hs 766T, CFPAC-1, PANC-1), normal pancreatic duct epithelial cell line (HPDE)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PTN
Associated microRNA: hsa-miR-137-3p
Biological function: promote proliferation, migration and invasion
Molecular mechanism: hsa-miR-137-3p/PTN axis
Survival: poor
Supported No.:
 2
Description:

knockdown of circ-LDLRAD3 repressed the proliferation, migration and invasion of pancreatic cancer cells through miR-137-3p/PTN axis.
Other information
Title:

Downregulation of circular RNA circ-LDLRAD3 suppresses pancreatic cancer progression through miR-137-3p/PTN axis.

Journal: Life Sci
Published: 2019/9/16
PubMed ID: 31521692