circRNA basic information
circBase ID: -
Name: hsa_circ_FBXW7
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: NEK2, mTOR, PTEN
Associated microRNA: -
Biological function: inhibite proliferation, migration and invasion
Molecular mechanism: reversing the expressions of NEK2, mTOR, and PTEN
Survival: -
Supported No.:
 3
Description:

circ-FBXW7 plays a major role in controlling the progression of CRC through NEK2, mTOR, and PTEN signaling pathways and may be a potential therapeutic target for CRC treatment.
Other information
Title:

FBXW7 circular RNA regulates proliferation, migration and invasion of colorectal carcinoma through NEK2, mTOR, and PTEN signaling pathways in vitro and in vivo.

Journal: BMC Cancer
Published: 2019/9/15
PubMed ID: 31519156