circRNA basic information
circBase ID: -
Name: hsa_circ_PITX1
Synonym: circ-PITX1
Host Gene: hsa-miR-379-5p
 
 
 
Disease basic information
DO ID:
 3073
DO name: brain glioblastoma multiforme
Disease details: glioblastoma
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MAP3K2
Associated microRNA: hsa-miR-379-5p
Biological function: enhanced proliferation and inhibited apoptosis
Molecular mechanism: sponging hsa-miR-379-5p to elevate MAP3K2 expression
Survival: -
Supported No.:
 3
Description:

circ-PITX1 exerted as a competing endogenous RNA (ceRNA) in glioblastoma by sponging miR-379-5p to elevate MAP3K2 expression.
Other information
Title:

Circular RNA circ-PITX1 promotes the progression of glioblastoma by acting as a competing endogenous RNA to regulate miR-379-5p/MAP3K2 axis.

Journal: Eur J Pharmacol
Published: 2019/9/8
PubMed ID: 31493405