circRNA basic information
circBase ID: hsa_circ_0010729
Name: hsa_circ_HSPG2
Synonym: circ_0010729
Host Gene: hsa-miR-145-5p
 
 
 
Disease basic information
DO ID:
1287
DO name: cardiovascular system disease
Disease details: myocardial ischemia
Species: human
Species details: human
Sample type: cell line
Sample type details: human cardiomyocytes (HCM)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DS
Associated gene: -
Associated microRNA: hsa-miR-145-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
1
Description:

silencing circ_0010729 activated mTOR and MEK/ERK pathways by up-regulating miR-145-5p.

Other information
Title:

Silencing circular RNA circ_0010729 protects human cardiomyocytes from oxygen-glucose deprivation-induced injury by up-regulating microRNA-145-5p.

Journal: Mol Cell Biochem
Published: 2019/9/5
PubMed ID: 31482388