circRNA basic information
circBase ID: -
Name: hsa_circ_ZKSCAN1
Synonym: circ-ZKSCAN1
Host Gene: hsa-miR-1178-3p
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human bladder cancer cell lines (T24, UM-UC-3, 5637, EJ, SV-HUC-1)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: p21
Associated microRNA: hsa-miR-1178-3p
Biological function: inhibits cell proliferation, migration, invasion and metastasis
Molecular mechanism: circ-ZKSCAN1 upregulated p21 expression by sponging hsa-miR-1178-3p
Survival: better
Supported No.:
 1
Description:

Circ-ZKSCAN1 acts as a tumor suppressor via a novel circ-ZKSCAN1/miR-1178-3p/p21 axis.
Other information
Title:

Circular RNA circ-ZKSCAN1 inhibits bladder cancer progression through miR-1178-3p/p21 axis and acts as a prognostic factor of recurrence.

Journal: Mol Cancer
Published: 2019/9/5
PubMed ID: 31481066