circRNA basic information
circBase ID: hsa_circ_0088227
Name: hsa_circ_PAPPA
Synonym: -
Host Gene: hsa-miR-384
 
 
 
Disease basic information
DO ID:
 10591
DO name: pre-eclampsia
Disease details: preeclampsia
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: STAT3
Associated microRNA: hsa-miR-384
Biological function: suppresses the proliferation and invasion
Molecular mechanism: hsa-miR-384/STAT3
Survival: -
Supported No.:
 2
Description:

down-regulation of circPAPPA facilitates the onset and development of PE by suppressing trophoblast cells, with involvement of the miR-384/STAT3 signaling pathway.
Other information
Title:

Down-regulated circPAPPA suppresses the proliferation and invasion of trophoblast cells via the miR-384/STAT3 pathway.

Journal: Biosci Rep
Published: 2019/8/21
PubMed ID: 31427481