circRNA basic information
circBase ID: -
Name: hsa_circ_VAPA
Synonym: -
Host Gene: hsa-miR-377-3p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PSAP
Associated microRNA: hsa-miR-377-3p
Biological function: circVAPA was upregulated in HCC cell lines and circVAPA depletion was associated with decreased HCC cell proliferation
Molecular mechanism: promotes PSAP expression through sequestering hsa-miR-377-3p
Survival: -
Supported No.:
 2
Description:

circVAPA contributes to HCC cell proliferation through sponging miR-377-3p and thereby disinhibiting PSAP.
Other information
Title:

Circular RNA circVAPA Promotes Cell Proliferation in Hepatocellular Carcinoma.

Journal: Hum Gene Ther Clin Dev
Published: 2019/8/2
PubMed ID: 31368365