circRNA basic information
circBase ID: hsa_circ_0008450
Name: hsa_circ_CMTM3
Synonym: circ_0008450
Host Gene: hsa-miR-577
 
 
 
Disease basic information
DO ID:
 9261
DO name: nasopharynx carcinoma
Disease details: nasopharyngeal carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: NPC cells (HK-1, 5-8F, C666-1, SUNE-1, NP69)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CXCL9
Associated microRNA: hsa-miR-577
Biological function: promote cell proliferation and invasion
Molecular mechanism: reduced hsa-miR-577-mediated repression of CXCL9, resulting in facilitating the oncogenic functions of NPC
Survival: -
Supported No.:
 1
Description:

circ_0008450 acts as an oncogene in NPC cells through regulating miR-577/CXCL9 signaling.
Other information
Title:

Circular RNA circ_0008450 upregulates CXCL9 expression by targeting miR-577 to regulate cell proliferation and invasion in nasopharyngeal carcinoma.

Journal: Exp Mol Pathol
Published: 2019/7/26
PubMed ID: 31344361