circRNA basic information
circBase ID: -
Name: hsa_circ_PLK1
Synonym: circPLK1
Host Gene: hsa-miR-296-5p
 
 
 
Disease basic information
DO ID:
 60081
DO name: triple-receptor negative breast cancer
Disease details: triple-negative breast cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: normal mammary epithelial cell lines (MCF10A), breast cancer cell lines (MDAMB-468, MDA-MB-453, MDA-MB-231, HCC38, BT549)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-296-5p
Biological function: promote cell growth and invasion
Molecular mechanism: CircPLK1-hsa-miR-296-5p-PLK1 axis
Survival: poor
Supported No.:
 1
Description:

CircPLK1-miR-296-5p-PLK1 axis regulates tumor progression by ceRNA mechanism in TNBC.
Other information
Title:

CircPLK1 sponges miR-296-5p to facilitate triple-negative breast cancer progression.

Journal: Epigenomics
Published: 2019/7/25
PubMed ID: 31337246