circRNA basic information
circBase ID: hsa_circ_0058124
Name: hsa_circ_FN1
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 3969
DO name: thyroid gland papillary carcinoma
Disease details: papillary thyroid cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: NOTCH3, GATAD2A
Associated microRNA: -
Biological function: promotes papillary thyroid cancer tumorigenesis and invasiveness
Molecular mechanism: functions as a competing endogenous RNA to modulate miRNA-218-5p and its target gene NUMB expression, and consequently with repression of the NOTCH3/GATAD2A signaling axis
Survival: poor
Supported No.:
 2
Description:

hsa_circ_0058124/NOTCH3/GATAD2A axis which is critical for PTC tumorigenesis and invasiveness.
Other information
Title:

Hsa_circ_0058124 promotes papillary thyroid cancer tumorigenesis and invasiveness through the NOTCH3/GATAD2A axis.

Journal: J Exp Clin Cancer Res
Published: 2019/7/22
PubMed ID: 31324198