circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA_069718
Host Gene: -
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human BC cell lines (MCF-7, T47D, BT20, MDA-MB-468, MDA-MB-231), normal mammary epithelial cell lines (MCF-10A)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: promotes cell proliferation and invasion
Molecular mechanism: activating Wnt/beta-catenin pathway
Survival: poor
Supported No.:
 1
Description:

Our findings suggested that circRNA_069718 promoted TNBC progression via Wnt/beta-catenin pathway and could serve as a novel therapeutic target for TNBC treatment.
Other information
Title:

CircRNA_069718 promotes cell proliferation and invasion in triple-negative breast cancer by activating Wnt/beta-catenin pathway.

Journal: Eur Rev Med Pharmacol Sci
Published: 2019/7/13
PubMed ID: 31298383