circRNA basic information
circBase ID: -
Name: hsa_circ_ODC1
Synonym: -
Host Gene: hsa-miR-422a
 
 
 
Disease basic information
DO ID:
 768
DO name: retinoblastoma
Disease details: retinoblastoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human retinal pigment epithelial cell line (ARPE_19), RB cell lines (Y79, WERI_Rb1, SO_Rb50, HXO_RB44)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-422a
Biological function: promotes the proliferation of retinoblastoma
Molecular mechanism: positively regulat SKP2
Survival: -
Supported No.:
 1
Description:

SKP2, induced by circ_ODC1 and miR-422a, promotes RB proliferation. Our new findings in this research might expedite the discovery of novel prognostic markers and therapeutic targets of RB.
Other information
Title:

SKP2, positively regulated by circ_ODC1/miR-422a axis, promotes the proliferation of retinoblastoma.

Journal: J Cell Biochem
Published: 2019/7/13
PubMed ID: 31297892