circRNA basic information
circBase ID: -
Name: hsa_circ_PIP5K1A
Synonym: -
Host Gene: hsa-miR-600
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: LC cell lines (H1299, PC9, H1975, A549, H1650), normal lung epithelial cell line (BEAS_2B)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HIF-1alpha
Associated microRNA: hsa-miR-600
Biological function: promotes non-small cell lung cancer proliferation and metastasis
Molecular mechanism: circPIP5K1A/hsa-miR-600/HIF-1alpha axis
Survival: -
Supported No.:
 4
Description:

circPIP5K1A acted as a tumor promoter through a novel circPIP5K1A/miR-600/HIF-1alpha axis, which provides candidate markers and therapeutic targets for NSCLC.
Other information
Title:

Circular RNA circPIP5K1A promotes non-small cell lung cancer proliferation and metastasis through miR-600/HIF-1alpha regulation.

Journal: J Cell Biochem
Published: 2019/6/27
PubMed ID: 31241217