circRNA basic information
circBase ID: -
Name: -
Synonym: SCD-circRNA 2
Host Gene: -
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Huh7, HepG2, HCT-15, NCI-N87
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: RBM3
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Survival: poor
Supported No.:
 1
Description:

RBM3 overexpression was indicative of a short recurrence-free survival and poor overall survival for HCC patients. Furthermore, by modulating the RBM3 or SCD-circRNA 2 levels, we found that RBM3 promoted the HCC cell proliferation in a SCD-circRNA 2 dependent manner.
Other information
Title:

The RNA-binding protein RBM3 promotes cell proliferation in hepatocellular carcinoma by regulating circular RNA SCD-circRNA 2 production.

Journal: EBioMedicine
Published: 2019/6/27
PubMed ID: 31235426