circRNA basic information
circBase ID: hsa_circ_0104631
Name: -
Synonym: circ-0104631
Host Gene: -
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: CRC cell lines (SW480, LoVo, HCT116, HT29), normal control cell line (NCM460)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: promotes cell proliferation and invasion
Molecular mechanism: regulating PTEN/Akt/mTOR signaling pathway
Survival: poor
Supported No.:
 1
Description:

Circ-0104631 was highly expressed in CRC tissues. Furthermore, knockdown of Circ-0104631 could inhibit the growth and metastasis of CRC cells by regulating PTEN/Akt/mTOR signaling pathway.
Other information
Title:

Circ-0104631 promotes cell proliferation and invasion in colorectal cancer and predicts poor prognosis.

Journal: Eur Rev Med Pharmacol Sci
Published: 2019/6/19
PubMed ID: 31210299