circRNA basic information
circBase ID: -
Name: -
Synonym: hsa_circRNA_100290
Host Gene: hsa-miR-378a
 
 
 
Disease basic information
DO ID:
 50866
DO name: oral squamous cell carcinoma
Disease details: oral squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal oral keratinocyte cell line (KC), primary gingival KCs (ATCC_PCS_200_014), OSCC cell lines (CAL_27)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GLUT1
Associated microRNA: hsa-miR-378a
Biological function: promoting glycolysis and cell proliferation
Molecular mechanism: serves as a ceRNA to counteract hsa-miR-378a-mediated GLUT1 suppression
Survival: -
Supported No.:
 1
Description:

circRNA_100290 serves as a ceRNA to counteract miR-378a-mediated GLUT1 suppression, thus promoting glycolysis and cell proliferation in OSCC.
Other information
Title:

Circle RNA hsa_circRNA_100290 serves as a ceRNA for miR-378a to regulate oral squamous cell carcinoma cells growth via Glucose transporter-1 (GLUT1) and glycolysis.

Journal: J Cell Physiol
Published: 2019/6/13
PubMed ID: 31187488