circRNA basic information
circBase ID: -
Name: hsa_circ_CACTIN
Synonym: -
Host Gene: hsa-miR-331-3p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: GES1, BGC-823, MGC-803, SGC-7901
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: TGFBR1
Associated microRNA: hsa-miR-331-3p
Biological function: up-regulation promoted GC tumor proliferation, migration, invasion and EMT
Molecular mechanism: Sponging hsa-miR-331-3p and Regulating TGFBR1 Expression
Survival: -
Supported No.:
 1
Description:

The circCACTIN/miR-331-3p/TGFBR1 axis affected the proliferation, migration, invasion and EMT of GC through the mechanism of competing endogenous RNAs (ceRNA).
Other information
Title:

Circular RNA CircCACTIN Promotes Gastric Cancer Progression by Sponging MiR-331-3p and Regulating TGFBR1 Expression.

Journal: Int J Biol Sci
Published: 2019/6/12
PubMed ID: 31182928