circRNA basic information
circBase ID: -
Name: hsa_circ_MAN2B2
Synonym: -
Host Gene: hsa-miR-1205
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human glioma cancer cell line (U87, U251, A172, SHG44), normal human astrocytes cells (NHA)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: S100A8
Associated microRNA: hsa-miR-1205
Biological function: improve cell proliferation, invasion, and migration
Molecular mechanism: inhibiting hsa-miR-1205 and promoting the expression of S100A8
Survival: poor
Supported No.:
 1
Description:

circMAN2B2 could improve cell proliferation, invasion, and migration of the glioma by inhibiting miR-1205 and promoting the expression of S100A8.
Other information
Title:

Circular RNA circMAN2B2 facilitates glioma progression by regulating the miR-1205/S100A8 axis.

Journal: J Cell Physiol
Published: 2019/5/28
PubMed ID: 31131447