circRNA basic information
circBase ID: -
Name: hsa_circ_COL6A3
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: gastric cancer cell lines (BGC-823, MKN-45, AGS, SGC-7901), human normal gastric epithelial cell (GES-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: promoted cell proliferation, migration and apoptosis
Molecular mechanism: cancel hsa-miR-3064-5p-induced inhibitory effect on COL6A3
Survival: -
Supported No.:
 3
Description:

the present study indicated that overexpressed circCOL6A3 promoted cell proliferation, migration and apoptosis of gastric cancer through rescission of miR-3064-5p-induced inhibitory effect on COL6A3.
Other information
Title:

A circular RNA derived from COL6A3 functions as a ceRNA in gastric cancer development.

Journal: Biochem Biophys Res Commun
Published: 2019/5/28
PubMed ID: 31122696