circRNA basic information
circBase ID: hsa_circ_0068087
Name: hsa_circ_GNB4
Synonym: -
Host Gene: hsa-miR-197
 
 
 
Disease basic information
DO ID:
 4195
DO name: hyperglycemia
Disease details: hyperglycemia
Species: human
Species details: human
Sample type: cell line
Sample type details: human umbilical vein ECs (HUVECs)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TLR4, NLRP3
Associated microRNA: hsa-miR-197
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

these results suggest that downregulation of hsa_circ_0068087 ameliorates TLR4/NF-¦ĘB/NLRP3 inflammasome-mediated inflammation and endothelial cell dysfunction in the high glucose condition by sponging miR-197.
Other information
Title:

Downregulation of hsa_circ_0068087 ameliorates TLR4/NF-kappaB/NLRP3 inflammasome-mediated inflammation and endothelial cell dysfunction in high glucose conditioned by sponging miR-197.

Journal: Gene
Published: 2019/5/21
PubMed ID: 31108165