circRNA basic information
circBase ID: -
Name: -
Synonym: hsa_circ_001569
Host Gene: -
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal human breast epithelial cell line (MCF- 78 10A), human breast cancer cell lines (MCF-7, MDA-MB-468, MDAMB-231, MDA- 80 MB-453)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: promotes cell proliferation and metastasis
Molecular mechanism: activating PI3K-AKT signaling
Survival: poor
Supported No.:
 1
Description:

hsa_circ_001569 upregulation was associated with BC lymph-node metastasis, clinical stage, and poor prognosis. Hsa_circ_001569 might contribute to progression of BC by modulating PI3K-AKT pathway.
Other information
Title:

Hsa_circ_001569 is an unfavorable prognostic factor and promotes cell proliferation and metastasis by modulating PI3K-AKT pathway in breast cancer.

Journal: Cancer Biomark
Published: 2019/5/20
PubMed ID: 31104012