circRNA basic information
circBase ID: -
Name: hsa_circ_ACVR2A
Synonym: -
Host Gene: hsa-miR-626
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human BC cell lines (T24, UM-UC-3, RT4, J82, 5637, HT-1376, TCCSUP), immortalized normal uroepithelium cell line (SV-HUC-1)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: EYA4
Associated microRNA: hsa-miR-626
Biological function: suppresses bladder cancer cells proliferation and metastasis
Molecular mechanism: interact with hsa-miR-626 and act as a miRNA sponge to regulate EYA4 expression
Survival: better
Supported No.:
 1
Description:

circACVR2A functions as a tumor suppressor to inhibit bladder cancer cell proliferation and metastasis through miR-626/EYA4 axis.
Other information
Title:

Circular RNA ACVR2A suppresses bladder cancer cells proliferation and metastasis through miR-626/EYA4 axis.

Journal: Mol Cancer
Published: 2019/5/19
PubMed ID: 31101108