circRNA basic information
circBase ID: hsa_circ_0020397
Name: hsa_circ_DOCK1
Synonym: -
Host Gene: hsa-miR-138
 
 
 
Disease basic information
DO ID:
10941
DO name: intracranial aneurysm
Disease details: intracranial aneurysm
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: KDR
Associated microRNA: hsa-miR-138
Biological function: increased VSMC proliferation
Molecular mechanism: negatively correlated with hsa-miR-138
Survival: -
Supported No.:
1
Description:

decreased expression of circRNA_0020397 in IA may contribute to the decreased VSMC proliferation via increasing miR-138 expression and subsequently decreasing KDR expression.

Other information
Title:

Decreased expression of circ_0020397 in intracranial aneurysms may be contributing to decreased vascular smooth muscle cell proliferation via increased expression of miR-138 and subsequent decreased KDR expression.

Journal: Cell Adh Migr
Published: 2019/5/18
PubMed ID: 31096819