circRNA basic information
circBase ID: hsa_circ_0005075
Name: hsa_circ_EIF4G3
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human normal intestinal epithelial cell line (HCO), CRC cell types (SW480, SW620, HT29, HCT116, SW1116, LOVO)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: enhance the proliferation, migration, and invasion capacities
Molecular mechanism: activating Wnt/beta-catenin pathway
Survival: poor
Supported No.:
 2
Description:

Cellular studies indicated that circ_0005075 can enhance the proliferation, migration, and invasion capacities of CRC cells, thereby promoting tumor progression.
Other information
Title:

Hsa_circ_0005075 predicts a poor prognosis and acts as an oncogene in colorectal cancer via activating Wnt/beta-catenin pathway.

Journal: Eur Rev Med Pharmacol Sci
Published: 2019/5/14
PubMed ID: 31081084