circRNA basic information
circBase ID: -
Name: -
Synonym: rno_circ_0004002
Host Gene: rno-miR-342-5p
 
 
 
Disease basic information
DO ID:
 1285
DO name: rectal disease
Disease details: anorectal malformation
Species: rat
Species details: rat
Sample type: tissue, cell line
Sample type details: rat intestinal epithelial cells (HEK293T)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: Wnt3a
Associated microRNA: rno-miR-342-5p
Biological function: with promotion of proliferation, and suppression of apoptosis and epithelial-mesenchymal transition (EMT)
Molecular mechanism: targeting miR-342-5p and Wnt3a
Survival: -
Supported No.:
 1
Description:

our study shed light on the regulatory mechanism of rno_circ_0004002 in cell proliferation, apoptosis, and EMT via sponging miR-342-5p, which downregulated the Wnt3a expression in anorectal development.
Other information
Title:

Circular RNA rno_circ_0004002 regulates cell proliferation, apoptosis, and epithelial-mesenchymal transition through targeting miR-342-5p and Wnt3a in anorectal malformations.

Journal: J Cell Biochem
Published: 2019/5/11
PubMed ID: 31074015