circRNA basic information
circBase ID: -
Name: hsa_circ_ZNF292
Synonym: cZNF292
Host Gene: -
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatoma
Species: human
Species details: human
Sample type: cell line
Sample type details: human hepatocellular carcinoma cells (SMMC7721)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DS
Associated gene: -
Associated microRNA: -
Biological function: promote cell proliferation, vasculogenic mimicry, and radioresistance
Molecular mechanism: Knockdown of cZNF292 increased SRY (sex determining region Y)-box 9 (SOX9) nuclear translocation, subsequently reduced Wnt/beta-catenin pathway activity
Survival: -
Supported No.:
 2
Description:

A novel mechanism of cZNF292 in enhancing hypoxic tumor cell radiosensitivity.
Other information
Title:

Knockdown of cZNF292 suppressed hypoxic human hepatoma SMMC7721 cell proliferation, vasculogenic mimicry, and radioresistance.

Journal: Cell Signal
Published: 2019/4/28
PubMed ID: 31028816