circRNA basic information
circBase ID: hsa_circ_0068871
Name: hsa_circ_FGFR3
Synonym: -
Host Gene: hsa-miR-181a-5p
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human BCa cell lines (T24, UMUC3, EJ, J82), immortalized human normal bladder epithelial cell line (SV-HUC-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FGFR3
Associated microRNA: hsa-miR-181a-5p
Biological function: facilitated cell proliferation, migratory
Molecular mechanism: regulates FGFR3 expression and activates STAT3 by targeting hsa-miR-181a-5p
Survival: -
Supported No.:
 1
Description:

Hsa_circ_0068871 regulates the miR-181a-5p/FGFR3 axis and activates STAT3 to promote BCa progression, and it may serve as a potential biomarker.
Other information
Title:

Circular RNA hsa_circ_0068871 regulates FGFR3 expression and activates STAT3 by targeting miR-181a-5p to promote bladder cancer progression.

Journal: J Exp Clin Cancer Res
Published: 2019/4/20
PubMed ID: 30999937