circRNA basic information
circBase ID: -
Name: hsa_circ_RASSF2
Synonym: circRASSF2
Host Gene: hsa-miR-302b-3p
 
 
 
Disease basic information
DO ID:
 2876
DO name: laryngeal squamous cell carcinoma
Disease details: laryngeal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal human bronchial epithelial cell line (NHBEC), human laryngeal cancer cell lines (TU686, TU177, Hep-2, LSC-1)
circRNA-disease information
Detected method:
M
Detected method confidence Low
Expression pattern:
UP
Associated gene: IGF-1R
Associated microRNA: hsa-miR-302b-3p
Biological function: facilitated cell proliferation, migratory
Molecular mechanism: regulating the hsa-miR-302b-3p/IGF-1R axis
Survival: -
Supported No.:
 1
Description:

these data suggest that circRASSF2 is a central component linking circRNAs to progression of LSCC via an miR-302b-3p/IGF-1R axis.
Other information
Title:

CircRASSF2 promotes laryngeal squamous cell carcinoma progression by regulating the miR-302b-3p/IGF-1R axis.

Journal: Clin Sci (Lond)
Published: 2019/4/18
PubMed ID: 30992382