circRNA basic information
circBase ID: -
Name: hsa_circ_DENND2A
Synonym: -
Host Gene: hsa-miR-625-5p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: cell line
Sample type details: normal human astrocyte line (SVGp12), human glioma cell lines (U87MG, A172)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-625-5p
Biological function: promotes glioma aggressiveness
Molecular mechanism: sponging hsa-miR-625-5p
Survival: -
Supported No.:
 1
Description:

circDENND2A is required for the hypoxia-induced malignancy of glioma cells and functions by sponging miR-625-5p.
Other information
Title:

Hypoxia-associated circDENND2A promotes glioma aggressiveness by sponging miR-625-5p.

Journal: Cell Mol Biol Lett
Published: 2019/4/17
PubMed ID: 30988674