circRNA basic information
circBase ID: hsa_circ_0004370
Name: hsa_circ_PRRX1
Synonym: -
Host Gene: hsa-miR-1294
 
 
 
Disease basic information
DO ID:
 5041
DO name: esophageal cancer
Disease details: esophageal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human EC cell lines (Eca-109, TE-1 , KYSE-150)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: LASP1
Associated microRNA: hsa-miR-1294
Biological function: facilitated cell proliferation, migratory and invasive capacities
Molecular mechanism: via hsa-miR-1294/LASP1 axis
Survival: -
Supported No.:
 1
Description:

The results present here suggest that hsa_circ_0004370 functions as an oncogene on cell proliferation, apoptosis, and invasion via miR-1294/LASP1 axis.
Other information
Title:

Hsa_circ_0004370 promotes esophageal cancer progression through miR-1294/LASP1 pathway.

Journal: Biosci Rep
Published: 2019/4/17
PubMed ID: 30988074