circRNA basic information
circBase ID: -
Name: hsa_circ_CSPP1
Synonym: -
Host Gene: hsa-miR-1236-3p
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human ovarian cancer cell lines (CAOV3, A2780, OVCAR3)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-1236-3p
Biological function: promotes proliferation, invasion and migration
Molecular mechanism: acting as a hsa-miR-1236-3p sponge, circ-CSPP1 impairs the inhibitory effect of hsa-miR-1236-3p on ZEB1
Survival: -
Supported No.:
 1
Description:

our findings suggest that by acting as a miR-1236-3p sponge, circ-CSPP1 impairs the inhibitory effect of miR-1236-3p on ZEB1, which subsequently promotes EMT and OC development.
Other information
Title:

circ-CSPP1 promotes proliferation, invasion and migration of ovarian cancer cells by acting as a miR-1236-3p sponge.

Journal: Biomed Pharmacother
Published: 2019/4/10
PubMed ID: 30965236