circRNA basic information
circBase ID: -
Name: hsa_circ_DLST
Synonym: -
Host Gene: hsa-miR-502-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: gastric epithelial cell line (GES-1), GC cell lines (MGC-803, BGC-823, SGC-7901, HGC-27, AGS, MKN-45, MKN-28)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: NRAS, MEK1, ERK1, ERK2
Associated microRNA: hsa-miR-502-5p
Biological function: facilitated cell proliferation, migratory and invasive capacities
Molecular mechanism: sponging hsa-miR-502-5p and activating the NRAS/MEK1/ERK1/2 signaling
Survival: -
Supported No.:
 2
Description:

CircDLST promotes the tumorigenesis and metastasis of GC cells by sponging miR-502-5p to activate the NRAS/MEK1/ERK1/2 signaling.
Other information
Title:

CircDLST promotes the tumorigenesis and metastasis of gastric cancer by sponging miR-502-5p and activating the NRAS/MEK1/ERK1/2 signaling.

Journal: Mol Cancer
Published: 2019/4/7
PubMed ID: 30953514