circRNA basic information
circBase ID: -
Name: hsa_circ_HDAC9
Synonym: -
Host Gene: hsa-miR-138
 
 
 
Disease basic information
DO ID:
 10652
DO name: Alzheimer disease
Disease details: Alzheimer disease
Species: human
Species details: human
Sample type: PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: Sirtuin-1
Associated microRNA: hsa-miR-138
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

The circHDAC9/miR-138/Sirt1 pathway mediates synaptic function and APP processing in AD, providing a potential therapeutic target for its treatment.
Other information
Title:

Circular HDAC9/microRNA-138/Sirtuin-1 Pathway Mediates Synaptic and Amyloid Precursor Protein Processing Deficits in Alzheimer Disease.

Journal: Neurosci Bull
Published: 2019/3/20
PubMed ID: 30887246